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First, previously published data is systematically analysed regarding the gonadotoxicity of chemo and radiotherapies in cancer patients.

Second, a prospective cohort study is performed to collect the following data in the study registry REDCap: ovarian function is evaluated by analysing AMH, FSH, LH and E2 concentrations and testicular function by analysing sperm parameters and total testosterone, just before and 12-15 months after the end of the gonadotoxic therapy (short term fertility). These fertility parameters, as well as the history of conceptions, will be collected 5 and 10 years after gonadotoxic therapies (long term fertility).

Furthermore, proportion of patients undergoing fertility preserving methods, efficacy and satisfaction with these methods will be analysed.

Third, the data will be merged to create the internet based data platform FertiTOX. The platform will be structured according to the ICD classification of cancer diseases and will be easily accessible using a specific App.

A description of the study has been submitted and will be found in the website menu “Papers published”.

Material such as paper versions of the REDCap study registry can also be downloaded (see PDF files below):

• REDCap registry: Documentation in females before gonadotoxic therapy
• REDCap registry: Documentation in males before gonadotoxic therapy
• REDCap registry: Documentation in females 12-15 months after the end of gonadotoxic therapy
• REDCap registry: Documentation in males 12-15 months after the end of gonadotoxic therapy

The paper versions can be used in the outpatient clinic to collect data to be added to the registry later.

Compact paper versions in German of the REDCap study registry can also be downloaded (see PDF files below):

• REDCap registry: Documentation in females before gonadotoxic therapy
• REDCap registry: Documentation in males before gonadotoxic therapy
• Disease list (ICD-10 coded, in English)

The English, French and Italian versions will be posted shortly.